-
Product Name
TLR7 Rabbit pAb
-
Gene ID
51284
-
SwissProt ID
Q9NYK1
-
Gene Name
TLR7
-
Alternative Names
TLR-7; PRO285; TLR 7; TLR7_HUMAN; Toll like receptor 7; Toll-like receptor 7; UNQ248.
-
Background
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
-
Research Field
Immunology
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human,Rat
-
Application
WB,ELISA
-
Dilution Ratio
WB: 1/500-1/1000 ELISA: 1/5000-1/10000
-
Molecular Weight
Calculated MW: 121kDa
-
Clonality
Polyclonal
-
Clonality No.
-
-
Isotype
IgG
-
Immunogen
Recombinant human TLR7 protein
-
Purification
affinity purified by Protein A
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
-
Storage
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.