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Product Name
Phospho-Dnmt3a (Ser390 + Ser393) Rabbit pAb
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Gene ID
1788
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SwissProt ID
Q9Y6K1
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Gene Name
DNMT3A
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Alternative Names
Dnmt3a (phospho S390 + S393); Dnmt3a (phospho Ser390 + Ser393);
p-Dnmt3a (phospho S390 + S393);
DNA (cytosine 5) methyltransferase 3 alpha;
DNA (cytosine 5) methyltransferase 3A;
DNA (cytosine-5)-methyltransferase 3A;
DNA cytosine methyltransferase 3A2;
DNA methyltransferase 3a;
DNA methyltransferase HsaIIIA;
DNA MTase HsaIIIA;
DNM3A_HUMAN;
DNMT 3a;
DNMT;
Dnmt3a;
DNMT3A2;
M.HsaIIIA;
MCMT;
OTTHUMP00000201149.
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Background
Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development. Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2 and DNMT3. DNMT1 is constitutively expressed in proliferating cells and functions as a maintenance methyltransferase, transferring proper methylation patterns to newly synthesized DNA during replication.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,IHC-P,ELISA
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/5000-1/10000
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Molecular Weight
Calculated MW: 102kDa
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Clonality
Polyclonal
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Clonality No.
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Isotype
IgG
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Immunogen
KLH conjugated Synthesised phosphopeptide derived from human Dnmt3a around the phosphorylation site of Ser390 + Ser393
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Purification
affinity purified by Protein A
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
Liquid
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Buffer System
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Storage
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.