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Product Name
5-hydroxymethylcytosine (5-hmC) Rabbit pAb
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Gene ID
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SwissProt ID
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Gene Name
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Alternative Names
5-hmC; 5hmc; 5-HydroxyMethyl cytidine; hm5c
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Background
5-Hydroxymethylcytosine (5-hmC) is a modified base form of cytosine recently found in Human/mouse brain and inembryonic stem cells. This DNA pyrimidine nitrogen base can be generated by oxidation of 5-methylcytosine, a reaction mediated by the ten-eleven translocation (TET) family of the 5-mC hydroxylases. The function of this base is still not elucidated but it is believed to play an important role in switching genes on and off.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human, Mouse, Rat, Other (Wide Range Predicted)
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Application
DB,ELISA
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Dilution Ratio
DB: 1/500-1/2000 ELISA: 1/5000-1/10000
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Molecular Weight
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Clonality
Polyclonal Antibody
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Clonality No.
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Isotype
IgG
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Immunogen
Chemical compounds corresponding to 5-hydroxymethylcytidine / hm5C.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 0.01% thimerosal,50% glycerol,pH7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.