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货号： 381968

别名： TR; TR1; TXNR; TRXR1; GRIM-12

应用： WB,IHC-P,ICC/IF,FC,IP

反应种属： Human,Mouse,Rat

目录价格：

RMB(含税报价)

数量： - + （库存件）

查看代理商预计货期：现货说明书PDF

产品详情

Product Name

Thioredoxin Reductase 1 Rabbit pAb
Gene ID

7296
SwissProt ID

Q16881
Gene Name

TXNRD1
Alternative Names

TR; TR1; TXNR; TRXR1; GRIM-12
Background

Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
Research Field

Signal Transduction
Product Categories

Primary antibody
Host

Rabbit
Reactivity

Human,Mouse,Rat
Application

WB,IHC-P,ICC/IF,FC,IP
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Molecular Weight

Calculated MW: 71 kDa; Observed MW: 55 kDa
Clonality

Polyclonal Antibody
Clonality No.

-
Isotype

IgG
Immunogen

A synthesized peptide derived from human TXNRD1
Purification

Affinity Chromatography
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

引用文献更多完整详情

标题： Jolkinolide B targets thioredoxin and glutathione systems to induce ROS-mediated paraptosis and apoptosis in bladder cancer cells

样本种属： Human

杂志： CANCER LETTERS

应用： WB

IF： 8.679

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