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Product Name
SH3BP4A Rabbit pAb
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Gene ID
403082
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SwissProt ID
Q1LVQ2
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Gene Name
SH3BP4A
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Alternative Names
SH3 domain-binding protein 4-A, sh3bp4a, sh3bp4
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Background
Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane. Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy (By similarity).
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Research Field
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Zebrafish
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Application
WB
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Dilution Ratio
WB: 1/1000
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Molecular Weight
Calculated MW:108 kDa; Observed MW: 108 kDa
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Clonality
Polyclonal Antibody
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Clonality No.
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Isotype
IgG
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Immunogen
This DANRE sh3bp4a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide from the N-terminal region of DANRE sh3bp4a.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 0.09% sodium azide, pH 7.3.
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Storage
Store at 2-8°C for up to 2 weeks. store at -20°C for long term storage in small aliquots. Avoid freeze/thaw cycles.