产品详情
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Product Name
ChREBP (4E5) Mouse mAb
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Gene ID
51085
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SwissProt ID
Q9NP71
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Gene Name
MLXIPL
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Alternative Names
MIO; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14
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Background
This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
ICC/IF
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Dilution Ratio
IF: 1/50-1/200
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Molecular Weight
-
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Clonality
Monoclonal Antibody
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Clonality No.
4E5-10B8-4A3
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Isotype
IgG1
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Immunogen
Purified recombinant fragment of human MLXIPL expressed in E. Coli.
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Purification
Ascitic Fluid
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Ascitic fluid containing 0.03% sodium azide.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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样本种属:
Human
杂 志:
BIOORGANIC CHEMISTRY
应用:
WB
IF:
5.1
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