-
Product Name
RING1 Mouse mAb
-
Gene ID
6015
-
SwissProt ID
Q06587
-
Gene Name
RING1
-
Alternative Names
Ring1A; Ring1; RING1A; Rnf1
-
Background
Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.
-
Research Field
Epigenetics and Nuclear Signaling
-
Product Categories
Primary antibody
-
Host
Mouse
-
Reactivity
Human
-
Application
WB,IHC-P,FC
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200 FC: 1/50-1/100
-
Molecular Weight
Calculated MW: 42 kDa; Observed MW: 42 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
7D12-G1-B7
-
Isotype
IgG1
-
Immunogen
Purified recombinant fragment of human Ring1 expressed in E. Coli.
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Purified antibody in PBS with 0.05% sodium azide.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.