-
Product Name
Phospho-Tau (Thr212) Rabbit pAb
-
Gene ID
4137
-
SwissProt ID
P10636
-
Gene Name
MAPT
-
Alternative Names
Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau; MAPT; MAPTL; MTBT1; TAU
-
Background
Tau, also known as MAPT (microtubule-associated protein tau), MAPTL, MTBT1 or TAU, is a 758 amino acid protein that localizes to the cytoplasm, as well as to the cytoskeleton and the cell membrane, and contains four Tau/MAP repeats. Expressed in neuronal tissue and existing as multiple alternatively spliced isoforms, Tau functions to promote microtubule assembly and stability and is thought to be involved in the maintenance of neuronal polarity. Tau may also link microtubules with neural plasma membrane components and, addition to its role in microtubule stability, is also necessary for cytoskeletal plasticity.
-
Research Field
-
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human,Mouse,Rat
-
Application
WB, IHC-P
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/200
-
Molecular Weight
-
-
Clonality
Polyclonal Antibody
-
Clonality No.
-
-
Isotype
IgG
-
Immunogen
Synthetic phosphopeptide derived from human isoforms Tau-4 around the phosphorylation site of Threonine 212.
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Phosphorylated
-
Form
Liquid
-
Buffer System
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.