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Product Name
TCEAL1 Rabbit pAb
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Gene ID
9338
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SwissProt ID
Q15170
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Gene Name
TCEAL1
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Alternative Names
TCEA-like protein 1; TCEAL1; pp21; SIIR;
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Background
TCEAL1 (transcription elongation factor A (SII) protein 3), also known as p21, SIIR or pp21, is a member of the TFS-II family. Transcription elongation factors of the TFS-II family are responsible for releasing RNA polymerase II (Pol II) from transcriptional arrest. DNA arresting sites can result in locked ternary complexes if elongating RNA polymerases are trapped. Transcription elongation factors function to activate the intrinsic RNA cleavage activity of RNA polymerases. This allows the RNA polymerase to cleave the nascent transcript, thereby forming a new 3’-terminus to resume elongation. TCEAL1 is a 157 amino acid nuclear protein that is ubiquitously expressed. TCEAL1 may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA.
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Research Field
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB, IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/200
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Molecular Weight
Calculated MW: 18kDa
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Clonality
Polyclonal Antibody
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Clonality No.
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Isotype
IgG
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Immunogen
Synthetic peptide corresponding to Human TCEAL1.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.