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货号： 220550

别名： BMR2; PPH1; BMPR3; BRK-3; T-ALK; BMPR-II; FLJ41585; FLJ76945; BMPR2

应用： WB,IHC-P,ICC/IF

反应种属： Human,Mouse,Rat,Monkey

目录价格：

RMB(含税报价)

数量： - + （库存件）

查看代理商预计货期：3-4个工作日说明书PDF

产品详情

Product Name

BMPR2 (9A9) Mouse mAb
Gene ID

659
SwissProt ID

Q13873
Gene Name

BMPR2
Alternative Names

BMR2; PPH1; BMPR3; BRK-3; T-ALK; BMPR-II; FLJ41585; FLJ76945; BMPR2
Background

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. (provided by RefSeq)
Research Field

Signal Transduction
Product Categories

Primary antibody
Host

Mouse
Reactivity

Human,Mouse,Rat,Monkey
Application

WB,IHC-P,ICC/IF
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200
Molecular Weight

Calculated MW: 115 kDa; Observed MW: 115 kDa
Clonality

Monoclonal Antibody
Clonality No.

9A9-10A8-3E7
Isotype

IgG1
Immunogen

Purified recombinant fragment of human BMPR2 expressed in E. Coli.
Purification

Ascitic Fluid
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Ascitic fluid containing 0.03% sodium azide.
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

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