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货号： 250106

别名： CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH

应用： WB,IHC-F,IHC-P,ICC/IF

反应种属： Human,Mouse,Rat

目录价格：

RMB(含税报价)

数量： - + （库存件）

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产品详情

Product Name

Cleaved-Caspase 8 Mouse mAb
Gene ID

841
SwissProt ID

Q14790
Gene Name

CASP8
Alternative Names

CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH
Background

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit.
Research Field

Cell Biology
Product Categories

Primary antibody
Host

Mouse
Reactivity

Human,Mouse,Rat
Application

WB,IHC-F,IHC-P,ICC/IF
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Molecular Weight

Calculated MW: 55 kDa; Observed MW: 18，43,57 kDa
Clonality

Monoclonal Antibody
Clonality No.

4C2-3G4-5G7
Isotype

IgG1
Immunogen

Recombinant Protein of Caspase-8
Purification

Affinity Purified
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

引用文献更多完整详情

标题： Acquired semi-squamatization during chemotherapy suggests differentiation as a therapeutic strategy for bladder cancer

样本种属： Mouse

杂志： CANCER CELL

应用： WB

IF： 38.59

文献链接

标题： Royal jelly acid suppresses hepatocellular carcinoma tumorigenicity by inhibiting H3 histone lactylation at H3K9la and H3K14la sites

样本种属： Human

杂志： PHYTOMEDICINE

应用： WB

IF： 7.9

文献链接

标题： Network pharmacology and transcriptomic profiling elucidate the therapeutic effects of Ranunculus ternatus Thunb on liver fibrosis via MK3-NF-κB inhibition

样本种属： Human

杂志： Aging-US

应用： WB

IF： 5.2

文献链接

标题： Atg3 Overexpression Enhances Bortezomib-Induced Cell Death in SKM-1 Cell

样本种属： Human

杂志： PLoS One

应用： WB

IF： 3.057

文献链接