-
Product Name
ZFP106 Rabbit pAb
-
Gene ID
64397
-
SwissProt ID
Q9H2Y7
-
Gene Name
ZNF106
-
Alternative Names
SH3BP3; ZFP106; ZNF474
-
Background
RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.
-
Research Field
Epigenetics and Nuclear Signaling
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human,Mouse,Monkey
-
Application
WB,ELISA
-
Dilution Ratio
WB: 1/500-1/1000 ELISA: 1/10000
-
Molecular Weight
Calculated MW: 209 kDa; Observed MW: 209 kDa
-
Clonality
Polyclonal Antibody
-
Clonality No.
-
-
Isotype
IgG
-
Immunogen
The antiserum was produced against synthesized peptide derived from human ZFP106.
-
Purification
Affinity Chromatography
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.