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货号： 200964

别名： STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor

应用： WB

反应种属： Human,Mouse,Rat,Monkey,Hamster

目录价格：

RMB(含税报价)

数量： - + （库存件）

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产品详情

Product Name

STAT3 (4C8) Mouse mAb
Gene ID

6774
SwissProt ID

P40763
Gene Name

STAT3
Alternative Names

STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor
Background

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.
Research Field

Signal Transduction
Product Categories

Primary antibody
Host

Mouse
Reactivity

Human,Mouse,Rat,Monkey,Hamster
Application

WB
Dilution Ratio

WB: 1/500-1/1000
Molecular Weight

Calculated MW: 88 kDa; Observed MW: 88 kDa
Clonality

Monoclonal Antibody
Clonality No.

4C8-1C9-H8
Isotype

IgG1
Immunogen

Purified recombinant human STAT3 protein fragments expressed in E.coli
Purification

Affinity Purified
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

引用文献更多完整详情

标题： Therapeutic potential of a synthetic dual JAK1/TYK2 inhibitor in inflammatory bowel disease

样本种属： Human

杂志： INTERNATIONAL IMMUNOPHARMACOLOGY

应用： WB

IF： 5.6

文献链接

标题： Studies on blocking the JAK2/STAT3 signaling pathway with elastin peptides from skipjack tuna (Katsuwonus pelamis) bulbus cordis to alleviate osteoarthritis

样本种属： Human

杂志： Food Bioscience

应用： WB

IF： 5.2

文献链接

标题： Berberine induces SOCS1 pathway to reprogram the M1 polarization of macrophages via miR-155–5p in colitis-associated colorectal cancer

样本种属： Mouse

杂志： EUROPEAN JOURNAL OF PHARMACOLOGY

应用： WB

IF： 5.195

文献链接

标题： Shengxuening Extracted from Silkworm Excrement Mitigates Myelosuppression via SCF-Mediated JAK2/STAT3 Signaling