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货号： 200782

别名： MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein

应用： WB

反应种属： Human,Mouse,Rat,Monkey

目录价格：

RMB(含税报价)

数量： - + （库存件）

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产品详情

Product Name

p38 (5A1) Mouse mAb
Gene ID

1432
SwissProt ID

Q16539
Gene Name

MAPK14
Alternative Names

MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein
Background

Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6.
Research Field

Signal Transduction
Product Categories

Primary antibody
Host

Mouse
Reactivity

Human,Mouse,Rat,Monkey
Application

WB
Cited

WB (S. Sclerotiorum Wild-Type Strain Ha61); IHC-P (Mouse)
Dilution Ratio

WB: 1/500-1/1000
Molecular Weight

Calculated MW: 41 kDa; Observed MW: 41 kDa
Clonality

Monoclonal Antibody
Clonality No.

5A1-C5-F11
Isotype

IgG1
Immunogen

Purified recombinant human P38 MAPK Pprotein fragments expressed in E.coli.
Purification

Affinity Purified
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

引用文献更多完整详情

标题： Stiffened fibre-like microenvironment based on patterned equidistant micropillars directs chondrocyte hypertrophy

样本种属： Human,Mouse

杂志： Materials Today Bio

应用： WB,IHC

IF： 10.761

文献链接

标题： The SUMOylation of TAB2 mediated by TRIM60 inhibits MAPK/NF-κB activation and the innate immune response

样本种属： Mouse

杂志： Cellular & Molecular Immunology

应用： WB

IF： 8.484

文献链接

标题： CGRP Regulates Nucleus Pulposus Cell Apoptosis and Inflammation via the MAPK/NF-κB Signaling Pathways during Intervertebral Disc Degeneration

样本种属： Human

杂志： Oxidative Medicine and Cellular Longevity

应用： WB

IF： 6.543

文献链接

标题： Musashi-2 Deficiency Triggers Colorectal Cancer Ferroptosis by Downregulating the MAPK Signaling Cascade to Inhibit HSPB1 Phosphorylation

样本种属： Human

杂志： BIOLOGICAL PROCEDURES ONLINE

应用： WB

IF： 6.4

文献链接

标题： Extracellular Vesicles Released from Macrophages Infected with Mycoplasma pneumoniae Stimulate Proinflammatory Response via the TLR2-NF-&kappa||B/JNK Signaling Pathway

样本种属： Human

杂志： INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

应用： WB

IF： 6.208

文献链接

标题： Gamabufotalin Inhibits Osteoclastgenesis and Counteracts Estrogen-Deficient Bone Loss in Mice by Suppressing RANKL-Induced NF-κB and ERK/MAPK Pathways

样本种属： Mouse

杂志： Frontiers in Pharmacology

应用： WB

IF： 5.811

文献链接

标题： Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways

样本种属： Mouse,Human

杂志： Frontiers in Pharmacology

应用： WB

IF： 5.6

文献链接

标题： Zinc induces reactive astrogliosis through ERK dependent activation of Stat3 and promotes synaptic degeneration