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货号： 340629

别名： MYD88; Myeloid differentiation primary response protein MyD88

应用： WB,IHC-F,IHC-P,ICC/IF,ELISA

反应种属： Human,Mouse,Rat

目录价格：

RMB(含税报价)

数量： - + （库存件）

查看代理商预计货期：现货说明书PDF

产品详情

Product Name

MyD88 Rabbit pAb
Gene ID

4615
SwissProt ID

Q99836
Gene Name

MYD88
Alternative Names

MYD88; Myeloid differentiation primary response protein MyD88
Background

Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-κB and subsequent regulation of immune and inflammatory genes.
Research Field

Signal Transduction
Product Categories

Primary antibody
Host

Rabbit
Reactivity

Human,Mouse,Rat
Application

WB,IHC-F,IHC-P,ICC/IF,ELISA
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
Molecular Weight

Calculated MW: 33 kDa; Observed MW: 33 kDa
Clonality

Polyclonal Antibody
Clonality No.

-
Isotype

IgG
Immunogen

The antiserum was produced against synthesized peptide derived from human MyD88.
Purification

Affinity Purified
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

引用文献更多完整详情

标题： Zinc glycine chelate ameliorates DSS-induced intestinal barrier dysfunction via attenuating TLR4/NF-κB pathway in meat ducks

样本种属： Duck

杂志： Journal of Animal Science and Biotechnology

应用： WB

IF： 7

文献链接

标题： Extracellular Vesicles Released from Macrophages Infected with Mycoplasma pneumoniae Stimulate Proinflammatory Response via the TLR2-NF-&kappa||B/JNK Signaling Pathway

样本种属： Human

杂志： INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

应用： WB

IF： 6.208

文献链接

标题： β-Sitosterol Alleviates Neuropathic Pain by Affect Microglia Polarization through Inhibiting TLR4/NF-κB Signaling Pathway

样本种属： Rat

杂志： Journal of Neuroimmune Pharmacology

应用： WB

IF： 6.2

文献链接

标题： The Ameliorative Role of Lico A on Aflatoxin B1-Triggered Hepatotoxicity Partially by Activating Nrf2 Signal Pathway

样本种属： Mouse

杂志： JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

应用： WB

IF： 6.1

文献链接

标题： Activation of estrogen receptor α inhibits TLR4 signaling in macrophages and alleviates the instability of atherosclerotic plaques in the postmenopausal stage

样本种属： Mouse,Human

杂志： INTERNATIONAL IMMUNOPHARMACOLOGY

应用： IHC,IF,WB

IF： 5.714

文献链接

标题： Longdan Xiegan decoction ameliorates vulvovaginal candidiasis by inhibiting the NLRP3 inflammasome via the Toll-like receptor /MyD88 pathway

样本种属： ——

杂志： JOURNAL OF ETHNOPHARMACOLOGY

应用： WB

IF： 5.4

文献链接

标题： Activated AXL Protects Against Hepatic Ischemia-reperfusion Injury by Upregulating SOCS-1 Expression

样本种属： Mouse

杂志： TRANSPLANTATION

应用： WB

IF： 5.385

文献链接

标题： Echinacea purpurea (L.) Moench Polysaccharide Alleviates DSS-Induced Colitis in Rats by Restoring Th17/Treg Balance and Regulating Intestinal Flora

样本种属： Rat

杂志： Foods

应用： WB

IF： 5.2

文献链接

标题： Arsenic exposure induces small intestinal toxicity in mice by barrier damage and inflammation response via activating RhoA/ROCK and TLR4/Myd88/NF-κB signaling pathways

样本种属： Mouse

杂志： TOXICOLOGY LETTERS

应用： WB

IF： 3.5

文献链接

标题： Alpinia oxyphylla Miq. volatile oil ameliorates depressive behaviors and inhibits neuroinflammation in CUMS-exposed mice by inhibiting the TLR4-medicated MyD88/NF-κB signaling pathway

样本种属： Mouse

杂志： JOURNAL OF CHEMICAL NEUROANATOMY

应用： WB

IF： 3.097

文献链接

标题： Coptisine from Coptis chinensis inhibits production of inflammatory mediators in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells

样本种属： Mouse

杂志： EUROPEAN JOURNAL OF PHARMACOLOGY

应用： WB

IF： 2.73

文献链接