货号： 340097
别名： PYCARD; ASC; CARD5; TMS1; Apoptosis-associated speck-like protein containing a CARD; hASC; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1
应用： WB,IHC-F,IHC-P,ICC/IF,ELISA
反应种属： Human,Mouse,Rat
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：现货 说明书PDF
产品详情
  • Product Name
    ASC Rabbit pAb
  • Gene ID
    29108
  • SwissProt ID
    Q9ULZ3
  • Gene Name
    PYCARD
  • Alternative Names
    PYCARD; ASC; CARD5; TMS1; Apoptosis-associated speck-like protein containing a CARD; hASC; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1
  • Background
    TMS1 (target of methylation-induced silencing)/ASC (apoptosis-associated speck-like protein containing a CARD), also referred to as PYCARD and CARD5, is a 22-kDa pro-apoptotic protein containing an N-terminal pyrin domain (PYD) and a C-terminal caspase recruitment domain (CARD).
  • Research Field
    Cell Biology
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human,Mouse,Rat
  • Application
    WB,IHC-F,IHC-P,ICC/IF,ELISA
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
  • Molecular Weight
    Calculated MW: 22 kDa; Observed MW: 22 kDa
  • Clonality
    Polyclonal Antibody
  • Clonality No.
    -
  • Isotype
    IgG
  • Immunogen
    The antiserum was produced against synthesized peptide derived from human ASC.
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
引用文献 更多完整详情
标 题： The pyroptosis mechanism of ototoxicity caused by unconjugated bilirubin in neonatal hyperbilirubinemia
样本种属： Mouse
杂 志： BIOMEDICINE & PHARMACOTHERAPY
应用： WB
IF： 7.5
文献链接
标 题： Polysaccharides from Polygonatum cyrtonema Hua Reduce Depression-Like Behavior in Mice by Inhibiting Oxidative Stress-Calpain-1-NLRP3 Signaling Axis
样本种属： Mouse
杂 志： Oxidative Medicine and Cellular Longevity
应用： WB,IF
IF： 6.543
文献链接
标 题： Simvastatin Inhibits NLRP3 Inflammasome Activation and Ameliorates Lung Injury in Hyperoxia-Induced Bronchopulmonary Dysplasia via the KLF2-Mediated Mechanism
样本种属： Rat
杂 志： Oxidative Medicine and Cellular Longevity
应用： WB
IF： 6.543
文献链接
标 题： Tissue Renin-Angiotensin System (tRAS) Induce Intervertebral Disc Degeneration by Activating Oxidative Stress and Inflammatory Reaction
样本种属： Human
杂 志： Oxidative Medicine and Cellular Longevity
应用： WB
IF： 6.543
文献链接
标 题： Use of Steaming Process to Improve Biochemical Activity of Polygonatum sibiricum Polysaccharides against D-Galactose-Induced Memory Impairment in Mice
样本种属： Mouse
杂 志： INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
应用： WB
IF： 6.21
文献链接
标 题： Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway
样本种属： Mouse
杂 志： Neural Regeneration Research
应用： WB
IF： 6.1
文献链接
标 题： Interleukin-37 ameliorates atherosclerosis by regulating autophagy-mediated endothelial cell apoptosis and inflammation
样本种属： Mouse,Human
杂 志： INTERNATIONAL IMMUNOPHARMACOLOGY
应用： WB
IF： 5.714
文献链接
标 题： The HIF-1/ BNIP3 pathway mediates mitophagy to inhibit the pyroptosis of fibroblast-like synoviocytes in rheumatoid arthritis
样本种属： Human
杂 志： INTERNATIONAL IMMUNOPHARMACOLOGY
应用： WB
IF： 5.6
文献链接
标 题： Neuroprotective effects of Jie-du-huo-xue decoction on microglia pyroptosis after cerebral ischemia and Reperfusion——From the perspective of glial-vascular unit
样本种属： Rat
杂 志： JOURNAL OF ETHNOPHARMACOLOGY
应用： WB
IF： 5.4
文献链接
标 题： Polysaccharides from Polygonatum cyrtonema Hua prevent post-traumatic stress disorder behaviors in mice: Mechanisms from the perspective of synaptic injury, oxidative stress, and neuroinflammation
样本种属： Mouse
杂 志： JOURNAL OF ETHNOPHARMACOLOGY
应用： WB
IF： 5.4
文献链接
标 题： Taohong Siwu decoction reduces acute myocardial ischemia–reperfusion injury by promoting autophagy to inhibit pyroptosis
样本种属： Mouse
杂 志： JOURNAL OF ETHNOPHARMACOLOGY
应用： IF,WB
IF： 5.4
文献链接
标 题： Protective effect of the total flavonoids from Clinopodium chinense against LPS-induced mice endometritis by inhibiting NLRP3 inflammasome-mediated pyroptosis
样本种属： Mouse
杂 志： JOURNAL OF ETHNOPHARMACOLOGY
应用： IF,WB
IF： 5.195
文献链接
标 题： Toll-Like Receptor 9 Aggravates Pulmonary Fibrosis by Promoting NLRP3-Mediated Pyroptosis of Alveolar Epithelial Cells
样本种属： Mouse,Human
杂 志： INFLAMMATION
应用： WB
IF： 5.1
文献链接
标 题： Ursolic acid protects chondrocytes, exhibits anti-inflammatory properties via regulation of the NF-κB/NLRP3 inflammasome pathway and ameliorates osteoarthritis
样本种属： Rat
杂 志： BIOMEDICINE & PHARMACOTHERAPY
应用： WB
IF： 4.545
文献链接
标 题： The protective role of autophagy against arsenic trioxide-induced cytotoxicity and ROS-dependent pyroptosis in NCTC-1469 cells
样本种属： Mouse
杂 志： JOURNAL OF INORGANIC BIOCHEMISTRY
应用： WB
IF： 4.155
文献链接
标 题： ZBP1 promotes hepatocyte pyroptosis in acute liver injury by regulating the PGAM5/ROS pathway
样本种属： Mouse,Human
杂 志： Annals of Hepatology
应用： WB
IF： 3.8
文献链接
标 题： Tributyrin alleviates gut microbiota dysbiosis to repair intestinal damage in antibiotic-treated mice
样本种属： Mouse
杂 志： PLoS One
应用： WB
IF： 3.7
文献链接
标 题： Effects of evodiamine on ROS/TXNIP/NLRP3 pathway against gouty arthritis
样本种属： Rat
杂 志： NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
应用： WB
IF： 3.6
文献链接
标 题： Paeoniflorin Protects against ANIT-Induced Cholestatic Liver Injury in Rats via the Activation of SIRT1-FXR Signaling Pathway
样本种属： Rat
杂 志： Evidence-based Complementary and Alternative Medicine
应用： WB
IF： 2.63
文献链接
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