货号： 380773
别名： NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor; erythroid derived 2; like 2
应用： WB,IHC-P,ICC/IF,IP,ChIP
反应种属： Human,Mouse
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：现货 说明书PDF
产品详情
  • Product Name
    Nrf2 Rabbit pAb
  • Gene ID
    4780
  • SwissProt ID
    Q16236
  • Gene Name
    NFE2L2
  • Alternative Names
    NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor; erythroid derived 2; like 2
  • Background
    Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
  • Research Field
    Epigenetics and Nuclear Signaling
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human,Mouse
  • Application
    WB,IHC-P,ICC/IF,IP,ChIP
  • Cited
    WB (Fish,Rat,Duck,Pig,Catfish); IHC-P (Rat)
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 ChIP: 1/20
  • Molecular Weight
    Calculated MW: 68 kDa; Observed MW: 100 kDa
  • Clonality
    Polyclonal Antibody
  • Clonality No.
    -
  • Isotype
    IgG
  • Immunogen
    A synthesized peptide derived from human Nrf2
  • Purification
    Affinity Chromatography
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
引用文献 更多完整详情
标 题： The MT1 receptor as the target of ramelteon neuroprotection in ischemic stroke
样本种属： Mouse
杂 志： JOURNAL OF PINEAL RESEARCH
应用： WB
IF： 10.3
文献链接
标 题： Poly (betulinic Acid) Nanoparticles Loaded with Bfgf Improve Functional Recovery After Spinal Cord Injury
样本种属： Mouse,Rat
杂 志： Advanced Healthcare Materials
应用： WB
IF： 10
文献链接
标 题： Polydopamine-loaded prunetin nanomaterials activate DRD2 to reduce UV-induced inflammation by stabilizing and promoting Nrf2 nuclear translocation
样本种属： Mouse
杂 志： Acta Biomaterialia
应用： WB
IF： 9.7
文献链接
标 题： Identification of antioxidant peptides targeting Keap1-Nrf2-ARE pathway from in vitro digestion of pork sausage with partial substitution of NaCl by KCl
样本种属： Human
杂 志： FOOD RESEARCH INTERNATIONAL
应用： WB
IF： 8.1
文献链接
标 题： Sodium butyrate protects against rotavirus-induced intestinal epithelial barrier damage by activating AMPK-Nrf2 signaling pathway in IPEC-J2 cells
样本种属： Pig
杂 志： INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
应用： WB
IF： 8
文献链接
标 题： Dioscin alleviates Alzheimer's disease through regulating RAGE/NOX4 mediated oxidative stress and inflammation
样本种属： Human,Mouse
杂 志： BIOMEDICINE & PHARMACOTHERAPY
应用： WB
IF： 7.419
文献链接
标 题： Ferroptosis of macrophages facilitates bone loss in apical periodontitis via NRF2/FSP1/ROS pathway
样本种属： Mouse，Human
杂 志： FREE RADICAL BIOLOGY AND MEDICINE
应用： IHC
IF： 7.4
文献链接
标 题： 13-oxyingenol dodecanoate derivatives induce mitophagy and ferroptosis through targeting TMBIM6 as potential anti-NSCLC agents
样本种属： Human
杂 志： EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
应用： WB,IF
IF： 6.7
文献链接
标 题： Polysaccharides from Polygonatum cyrtonema Hua Reduce Depression-Like Behavior in Mice by Inhibiting Oxidative Stress-Calpain-1-NLRP3 Signaling Axis
样本种属： Mouse
杂 志： Oxidative Medicine and Cellular Longevity
应用： WB,IF
IF： 6.543
文献链接
标 题： Quercetin alleviates ethanol-induced hepatic steatosis in L02 cells by activating TFEB translocation to compensate for inadequate autophagy
样本种属： Human
杂 志： PHYTOTHERAPY RESEARCH
应用： WB
IF： 6.39
文献链接
标 题： Lycopene Protects Intestinal Epithelium from Deoxynivalenol-Induced Oxidative Damage via Regulating Keap1/Nrf2 Signaling
样本种属： Mouse
杂 志： Antioxidants
应用： WB
IF： 6.313
文献链接
标 题： Use of Steaming Process to Improve Biochemical Activity of Polygonatum sibiricum Polysaccharides against D-Galactose-Induced Memory Impairment in Mice
样本种属： Mouse
杂 志： INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
应用： WB
IF： 6.21
文献链接
标 题： Dietary Leucine Improves Fish Intestinal Barrier Function by Increasing Humoral Immunity, Antioxidant Capacity, and Tight Junction
样本种属： Fish
杂 志： INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
应用： WB
IF： 6.208
文献链接
标 题： l-Carnosine Protects Against Deoxynivalenol-Induced Oxidative Stress in Intestinal Stem Cells by Regulating the Keap1/Nrf2 Signaling Pathway
样本种属： Mouse
杂 志： MOLECULAR NUTRITION & FOOD RESEARCH
应用： WB,IF
IF： 5.82
文献链接
标 题： Curcumin attenuates AFB1-induced duck liver injury by inhibiting oxidative stress and lysosomal damage
样本种属： Duck
杂 志： FOOD AND CHEMICAL TOXICOLOGY
应用： WB
IF： 5.6
文献链接
标 题： Heterocyclic aromatic amines induce Neuro-2a cells cytotoxicity through oxidative stress-mediated mitochondria-dependent apoptotic signals
样本种属： Mouse
杂 志： FOOD AND CHEMICAL TOXICOLOGY
应用： WB
IF： 5.572
文献链接
标 题： Polysaccharides from Polygonatum cyrtonema Hua prevent post-traumatic stress disorder behaviors in mice: Mechanisms from the perspective of synaptic injury, oxidative stress, and neuroinflammation
样本种属： Mouse
杂 志： JOURNAL OF ETHNOPHARMACOLOGY
应用： WB
IF： 5.4
文献链接
标 题： Melanin Nanoparticle-Actuated Redox-State Perturbation and Temporally Photoactivated Thermal Stress for Synergistic Tumor Therapy
样本种属： Human
杂 志： ACS Biomaterials Science & Engineering
应用： WB
IF： 5.395
文献链接
标 题： Gastrodin alleviates premature senescence of vascular endothelial cells by enhancing the Nrf2/HO-1 signalling pathway
样本种属： Human
杂 志： JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
应用： WB
IF： 5.3
文献链接
标 题： Clostridium butyricum MIYAIRI 588 alleviates periodontal bone loss in mice with diabetes mellitus
样本种属： Mouse
杂 志： ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
应用： WB
IF： 5.2
文献链接
标 题： Hesperidin mitigates oxidative stress-induced ferroptosis in nucleus pulposus cells via Nrf2/NF-κB axis to protect intervertebral disc from degeneration
样本种属： Human
杂 志： CELL CYCLE
应用： WB
IF： 5.173
文献链接
标 题： Transcutaneous Electrical Acupoint Stimulation Pretreatment Alleviates Cerebral Ischemia–Reperfusion Injury in Rats by Modulating Microglia Polarization and Neuroinflammation Through Nrf2/HO-1 Signaling Pathway
样本种属： Rat
杂 志： NEUROCHEMICAL RESEARCH
应用： WB
IF： 4.414
文献链接
标 题： Effects of dietary tryptophan on muscle growth, protein synthesis and antioxidant capacity in hybrid catfish Pelteobagrus vachelli♀ × Leiocassis longirostris♂
样本种属： Catfish
杂 志： BRITISH JOURNAL OF NUTRITION
应用： WB
IF： 3.718
文献链接
标 题： The study of an anoikis-related signature to predict glioma prognosis and immune infiltration
样本种属： Human
杂 志： JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
应用： IHC
IF： 3.6
文献链接
标 题： Excessive fluoride induces ovarian function impairment by regulating levels of ferroptosis in fluorosis women and ovarian granulosa cells
样本种属： Human
杂 志： REPRODUCTIVE TOXICOLOGY
应用： WB
IF： 3.3
文献链接
标 题： The anti-atherosclerotic effect of Paeonol against the lipid accumulation in macrophage-derived foam cells by inhibiting ferroptosis via the SIRT1/NRF2/GPX4 signaling pathway
样本种属： Mouse
杂 志： BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
应用： WB
IF： 3.1
文献链接
标 题： The role of ferroptosis in chronic intermittent hypoxia-induced cognitive impairment
样本种属： Rat
杂 志： Sleep and Breathing
应用： WB
IF： 2.66
文献链接
标 题： Paeoniflorin Protects against ANIT-Induced Cholestatic Liver Injury in Rats via the Activation of SIRT1-FXR Signaling Pathway
样本种属： Rat
杂 志： Evidence-based Complementary and Alternative Medicine
应用： WB
IF： 2.63
文献链接
标 题： The Alleviating Effect of Taxifolin on Deoxynivalenol-Induced Damage in Porcine Intestinal Epithelial Cells
样本种属： Porcine
杂 志： Veterinary Sciences
应用： WB
IF： 2.4
文献链接
标 题： Astragaloside IV protects LO2 cells from oxidative damage caused by radiation-induced bystander effect through Akt/Nrf2 pathway
样本种属： Human
杂 志： Toxicology Research
应用： IF
IF： 2.1
文献链接
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