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货号： 382600

别名： HIF1A; BHLHE78; MOP1; PASD8; Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS doma

应用： WB,IHC-F,IHC-P,ICC/IF,FC,IP

反应种属： Human

目录价格：

RMB(含税报价)

数量： - + （库存件）

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产品详情

Product Name

HIF1 alpha Rabbit pAb
Gene ID

3091
SwissProt ID

Q16665
Gene Name

HIF1A
Alternative Names

HIF1A; BHLHE78; MOP1; PASD8; Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS doma
Background

Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1.
Research Field

Cardiovascular
Product Categories

Primary antibody
Host

Rabbit
Reactivity

Human
Application

WB,IHC-F,IHC-P,ICC/IF,FC,IP
Cited

WB (Rat,Mouse); IF (Rat)
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Molecular Weight

Calculated MW: 93 kDa; Observed MW: 120 kDa
Clonality

Polyclonal Antibody
Clonality No.

-
Isotype

IgG
Immunogen

A synthetic peptide of human HIF-1-alpha
Purification

Affinity Purified
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

引用文献更多完整详情

标题： Hypoxia-Induced HIF-1&alpha|| Expression Promotes Neurogenic Bladder Fibrosis via EMT and Pyroptosis

样本种属： Rat

杂志： Cells

应用： IHC

IF： 7.666

文献链接

标题： BNIP3 mediates the different adaptive responses of fibroblast-like synovial cells to hypoxia in patients with osteoarthritis and rheumatoid arthritis

样本种属： Human

杂志： MOLECULAR MEDICINE

应用： WB

IF： 6.376

文献链接

标题： PHD3 mediates denervation skeletal muscle atrophy through Nf‐κB signal pathway

样本种属： Mouse

杂志： FASEB JOURNAL

应用： WB

IF： 5.192

文献链接