货号： 380172
别名： NFKB3; RELA; TF65; Transcription factor p65; p65; NFkB
应用： WB,IHC-P,ICC/IF,FC,IP
反应种属： Human,Mouse
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：现货 说明书PDF
产品详情
  • Product Name
    NF-KB p65 Rabbit pAb
  • Gene ID
    5970
  • SwissProt ID
    Q04206
  • Gene Name
    RELA
  • Alternative Names
    NFKB3; RELA; TF65; Transcription factor p65; p65; NFkB
  • Background
    NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm.
  • Research Field
    Cell Biology
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human,Mouse
  • Application
    WB,IHC-P,ICC/IF,FC,IP
  • Cited
    WB (Rat,Dog); IHC-P (Rat)
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
  • Molecular Weight
    Calculated MW: 60 kDa; Observed MW: 65 kDa
  • Clonality
    Polyclonal Antibody
  • Clonality No.
    -
  • Isotype
    IgG
  • Immunogen
    A synthesized peptide derived from human NF-κB p65
  • Purification
    Affinity Chromatography
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
引用文献 更多完整详情
标 题： Zein nanoparticles loaded with chloroquine improve functional recovery and attenuate neuroinflammation after spinal cord injury
样本种属： Rat
杂 志： CHEMICAL ENGINEERING JOURNAL
应用： WB
IF： 16.744
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标 题： 2D MoS2 Nanosheets Induce Ferroptosis by Promoting NCOA4-Dependent Ferritinophagy and Inhibiting Ferroportin
样本种属： Mouse,Human
杂 志： Small
应用： WB
IF： 15.153
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标 题： Alginate self-adhesive hydrogel combined with dental pulp stem cells and FGF21 repairs hemisection spinal cord injury via apoptosis and autophagy mechanisms
样本种属： Mouse
杂 志： CHEMICAL ENGINEERING JOURNAL
应用： WB
IF： 13.273
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标 题： Dioscin alleviates Alzheimer's disease through regulating RAGE/NOX4 mediated oxidative stress and inflammation
样本种属： Human,Mouse
杂 志： BIOMEDICINE & PHARMACOTHERAPY
应用： WB
IF： 7.419
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标 题： Oridonin attenuates lung inflammation and fibrosis in silicosis via covalent targeting iNOS
样本种属： Mouse
杂 志： BIOMEDICINE & PHARMACOTHERAPY
应用： WB
IF： 7.419
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标 题： Copper nanoparticles lead to reproductive dysfunction by affecting key enzymes of ovarian hormone synthesis and metabolism in female rats
样本种属： Rat
杂 志： ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
应用： WB
IF： 7.129
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标 题： Sirt4 deficiency promotes the development of atherosclerosis by activating the NF-κB/IκB/CXCL2/3 pathway
样本种属： Mouse
杂 志： ATHEROSCLEROSIS
应用： IF,WB
IF： 6.847
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标 题： Black phosphorus quantum dots induce myocardial inflammatory responses and metabolic disorders in mice
样本种属： Mouse
杂 志： Journal of Environmental Sciences
应用： WB
IF： 6.796
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标 题： Rapid access to icetexane diterpenes: Their protective effects against lipopolysaccharides-induced acute lung injury via PI3K/AKT/NF-κB axis in macrophages
样本种属： Mouse
杂 志： EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
应用： WB
IF： 6.7
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标 题： Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro
样本种属： Human
杂 志： PHYTOMEDICINE
应用： WB
IF： 6.656
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标 题： GMEB2 Promotes the Growth of Colorectal Cancer by Activating ADRM1 Transcription and NF-&kappa||B Signalling and Is Positively Regulated by the m6A Reader YTHDF1
样本种属： Mouse
杂 志： Cancers
应用： IF
IF： 6.6
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标 题： Tissue Renin-Angiotensin System (tRAS) Induce Intervertebral Disc Degeneration by Activating Oxidative Stress and Inflammatory Reaction
样本种属： Human
杂 志： Oxidative Medicine and Cellular Longevity
应用： WB
IF： 6.543
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标 题： Ulinastatin Ameliorates IL-1β-Induced Cell Dysfunction in Human Nucleus Pulposus Cells via Nrf2/NF-κB Pathway
样本种属： Human
杂 志： Oxidative Medicine and Cellular Longevity
应用： WB
IF： 6.543
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标 题： Extracellular Vesicles Released from Macrophages Infected with Mycoplasma pneumoniae Stimulate Proinflammatory Response via the TLR2-NF-&kappa||B/JNK Signaling Pathway
样本种属： Human
杂 志： INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
应用： WB
IF： 6.208
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标 题： TRAF-STOP alleviates osteoclastogenesis in periodontitis
样本种属： ——
杂 志： Frontiers in Pharmacology
应用： WB
IF： 5.988
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标 题： Therapeutic hyperthermia regulates complement C3 activation and suppresses tumor development through HSPA5/NFκB/CD55 pathway in nasopharyngeal carcinoma
样本种属： Human
杂 志： CLINICAL AND EXPERIMENTAL IMMUNOLOGY
应用： WB
IF： 5.732
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标 题： Calcitonin gene-related peptide ameliorates sepsis-induced intestinal injury by suppressing NLRP3 inflammasome activation
样本种属： Mouse
杂 志： INTERNATIONAL IMMUNOPHARMACOLOGY
应用： IF,WB
IF： 5.71
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标 题： DEAD-box helicase 1 inhibited CD8+ T cell antitumor activity by inducing PD-L1 expression in hepatocellular carcinoma
样本种属： Human
杂 志： CANCER SCIENCE
应用： IF,WB
IF： 5.7
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标 题： MicroRNA-181b attenuates lipopolysaccharide-induced inflammatory responses in pulpitis via the PLAU/AKT/NF-κB axis
样本种属： Human
杂 志： INTERNATIONAL IMMUNOPHARMACOLOGY
应用： WB
IF： 5.6
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标 题： Synthesis and evaluation of the anti-inflammatory activity of novel 8-quinolinesulfonamide derivatives as TLR4/MD-2 inhibitors with efficacy in adjuvant-induced arthritis
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IF： 5.275
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标 题： Macrophage immunity promotion effect of polysaccharide LGP-1 from Guapian tea via PI3K/AKT and NF-κB signaling pathway
样本种属： Mouse
杂 志： Journal of Functional Foods
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IF： 5.223
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标 题： Protective effect of the total flavonoids from Clinopodium chinense against LPS-induced mice endometritis by inhibiting NLRP3 inflammasome-mediated pyroptosis
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应用： IF,WB
IF： 5.195
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标 题： Bazedoxifene attenuates intestinal injury in sepsis by suppressing the NF-κB/NLRP3 signaling pathways
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杂 志： EUROPEAN JOURNAL OF PHARMACOLOGY
应用： WB
IF： 5.195
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标 题： Lentinan Attenuates Damage of the Small Intestinal Mucosa, Liver, and Lung in Mice with Gut-Origin Sepsis
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杂 志： Journal of Immunology Research
应用： WB,IHC
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杂 志： MEDIATORS OF INFLAMMATION
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IF： 4.711
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杂 志： Toxics
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标 题： Protective Effects of Phytic Acid on CCl4-Induced Liver Fibrosis in Mice
样本种属： Mouse
杂 志： JOURNAL OF FOOD BIOCHEMISTRY
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IF： 4
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标 题： Embelin attenuates lipopolysaccharide-induced acute kidney injury through the inhibition of M1 macrophage activation and NF-κB signaling in mice.
样本种属： Mouse
杂 志： Heliyon
应用： WB
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标 题： Inhibition of ALKBH5 inhibits inflammation and excessive proliferation by promoting TRIM13 m6A modifications in glomerular mesangial cells
样本种属： Mouse
杂 志： NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
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IF： 3.6
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标 题： Cyclic di-adenosine monophosphate regulates the osteogenic and adipogenic differentiation of hPDLSCs via MAPK and NF-κB signaling: c-di-AMP regulates the osteogenic and adipogenic differentiation of hPDLSCs
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应用： WB
IF： 3.511
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标 题： Unraveling the protective mechanisms of Chuanfangyihao against acute lung injury: Insights from experimental validation
样本种属： Rat
杂 志： Experimental and Therapeutic Medicine
应用： WB
IF： 2.7
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标 题： Regulation of endothelial cells on the osteogenic ability of bone marrow mesenchymal stem cells in peri-implantitis
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