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货号： 200784

别名： RAD9; hRAD9

应用： WB,IP

反应种属： Human,Mouse,Rat,Monkey

目录价格：

RMB(含税报价)

数量： - + （库存件）

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产品详情

Product Name

Rad9 Mouse mAb
Gene ID

5883
SwissProt ID

Q99638
Gene Name

RAD9A
Alternative Names

RAD9; hRAD9
Background

This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Field

Epigenetics and Nuclear Signaling
Product Categories

Primary antibody
Host

Mouse
Reactivity

Human,Mouse,Rat,Monkey
Application

WB,IP
Cited

IF (Human)
Dilution Ratio

WB: 1/500-1/1000 IP: 1/20
Molecular Weight

Calculated MW: 43 kDa; Observed MW: 60 kDa
Clonality

Monoclonal Antibody
Clonality No.

3A3-A7-F8
Isotype

IgG2b
Immunogen

Purified recombinant human RAD9A protein fragments expressed in E.coli
Purification

Affinity Purified
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

引用文献更多完整详情

标题： The DNA damage checkpoint protein RAD9A is essential for male meiosis in the mouse

样本种属： Mouse

杂志： JOURNAL OF CELL SCIENCE

应用： WB

IF： 5.877

文献链接

标题： Rad9a is required for spermatogonia differentiation in mice

样本种属： Mouse

杂志： Oncotarget

应用： WB

IF： 5.008