产品详情
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Product Name
APBA2 Mouse mAb
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Gene ID
321
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SwissProt ID
Q99767
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Gene Name
APBA2
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Alternative Names
X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091
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Background
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.
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Research Field
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
ICC/IF,ELISA
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Dilution Ratio
IF: 1/50-1/200 ELISA: 1/10000
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
2N6-D7-S4
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Isotype
Mouse IgG1
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Immunogen
Purified recombinant fragment of human APBA2 expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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