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Product Name
RF1 Mouse mAb
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Gene ID
2107
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SwissProt ID
P62495
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Gene Name
RF1
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Alternative Names
ERF; ETF1; ERF1; TB3-1; D5S1995; SUP45L1
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Background
This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X.
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Research Field
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,FC,ELISA
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Dilution Ratio
WB: 1/500-1/1000 FC: 1/50-1/100 ELISA: 1/10000
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Molecular Weight
Calculated MW: 49kDa;Observed MW: 49kDa
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Clonality
Monoclonal Antibody
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Clonality No.
8O5-D2-T5
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Isotype
Mouse IgG1
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Immunogen
Purified recombinant fragment of human RF1 expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.