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Product Name
ABCA1 Mouse mAb
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Gene ID
19
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SwissProt ID
O95477
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Gene Name
ABCA1
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Alternative Names
TGD; ABC1; CERP; ABC-1; HDLDT1; HPALP1; HDLCQTL13
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Background
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency.
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Research Field
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
ICC/IF,FC
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Dilution Ratio
IF: 1/50-1/200 FC: 1/50-1/100
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
6L5-T9-S6
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Isotype
Mouse IgG2a
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Immunogen
Purified recombinant fragment of human ABCA1 expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.