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货号： 222828

别名： XP3; RAD4; XPCC; p125

应用： WB,IHC-P,ICC/IF,FC,ELISA

反应种属： Human

目录价格：

RMB(含税报价)

数量： - + （库存件）

查看代理商预计货期：3-4个工作日说明书PDF

产品详情

Product Name

XPC Mouse mAb
Gene ID

7508
SwissProt ID

Q01831
Gene Name

XPC
Alternative Names

XP3; RAD4; XPCC; p125
Background

The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
Research Field

Epigenetics and Nuclear Signaling
Product Categories

Primary antibody
Host

Mouse
Reactivity

Human
Application

WB,IHC-P,ICC/IF,FC,ELISA
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200 FC: 1/50-1/100 ELISA: 1/10000
Molecular Weight

Calculated MW: 106kDa;Observed MW: 106kDa
Clonality

Monoclonal Antibody
Clonality No.

5Z2-I3-M5
Isotype

Mouse IgG1
Immunogen

Purified recombinant fragment of human XPC expressed in E. Coli.
Purification

Affinity Purified
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Purified antibody in PBS with 0.05% sodium azide
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

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