产品详情
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Product Name
Wnt5a Mouse mAb
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Gene ID
7474
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SwissProt ID
P41221
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Gene Name
WNT5A
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Alternative Names
hWNT5A
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Background
WNT5A: wingless-type MMTV integration site family, member 5A. Entrez Protein: NP_003383. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98%, 98% and 87% amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction.
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
IHC-P,ICC/IF
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Dilution Ratio
IHC: 1/100-1/200 IF: 1/50-1/200
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Molecular Weight
-
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Clonality
Monoclonal Antibody
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Clonality No.
4J5-Q2-H7
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Isotype
Mouse IgG1
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Immunogen
Purified recombinant fragment of WNT5A expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Ascitic fluid containing 0.03% sodium azide.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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