货号： 222823
别名： GUD; AWT1; WAGR; WT33; NPHS4; WIT-2
应用： WB,IHC-P,ICC/IF,FC,ELISA
反应种属： Human,Monkey
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    Wilms Tumor Protein Mouse mAb
  • Gene ID
    7490
  • SwissProt ID
    P19544
  • Gene Name
    WT1
  • Alternative Names
    GUD; AWT1; WAGR; WT33; NPHS4; WIT-2
  • Background
    This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.
  • Research Field
    Tags & Cell Markers
  • Product Categories
    Primary antibody
  • Host
    Mouse
  • Reactivity
    Human,Monkey
  • Application
    WB,IHC-P,ICC/IF,FC,ELISA
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200 FC: 1/50-1/100 ELISA: 1/10000
  • Molecular Weight
    Calculated MW: 49 kDa
  • Clonality
    Monoclonal Antibody
  • Clonality No.
    6Y8-E7-U1
  • Isotype
    Mouse IgG1
  • Immunogen
    Purified recombinant fragment of human WT1 expressed in E. Coli.
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    Purified antibody in PBS with 0.05% sodium azide
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
引用文献 更多完整详情
用户反馈
    推荐排序
  • 最近评价
  • 推荐排序
产品评论
评论内容：
商品评分
  • ★
  • ★
  • ★
  • ★
  • ★
微信扫码关注
Copyright ©2022 - 2023 成都正能生物技术有限责任公司
蜀ICP备13012294号-2
川公网安备 51012202001504号
  网站地图
犀牛云提供企业云服务