您现在的位置：首页 > 产品中心 > 抗体系列 > 精品一抗

货号： 250104

别名： ACTA2; ACTSA; ACTVS; GIG46; Actin; aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein; α-SMA

应用： WB,IHC-F,IHC-P,ICC/IF

反应种属： Human,Mouse,Rat

目录价格：

RMB(含税报价)

数量： - + （库存件）

查看代理商预计货期：现货说明书PDF

产品详情

Product Name

alpha Smooth Muscle Actin (3G2) Mouse mAb
Gene ID

59
SwissProt ID

P62736
Gene Name

ACTA2
Alternative Names

ACTA2; ACTSA; ACTVS; GIG46; Actin; aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein; α-SMA
Background

Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
Research Field

Signal Transduction
Product Categories

Primary antibody
Host

Mouse
Reactivity

Human,Mouse,Rat
Application

WB,IHC-F,IHC-P,ICC/IF
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Molecular Weight

Calculated MW: 42 kDa; Observed MW: 42 kDa
Clonality

Monoclonal Antibody
Clonality No.

3G2-2G9-4G5
Isotype

IgG1
Immunogen

Synthetic Peptide of α-SMA
Purification

Affinity Purified
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

展开更多

验证详情

展开更多

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

引用文献更多完整详情

标题： HucMSC exosomes attenuate partial bladder outlet obstruction-induced renal injury and cell proliferation via the Wnt/β-catenin pathway

样本种属： Mouse,Human

杂志： EUROPEAN JOURNAL OF PHARMACOLOGY

应用： WB

IF： 5.2

文献链接

标题： Upregulation of CYR61 by TGF-β and YAP signaling exerts a counter-suppression of hepatocellular carcinoma

样本种属： Human

杂志： JOURNAL OF BIOLOGICAL CHEMISTRY

应用： WB

IF： 4.8