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Product Name
MLH1 (4C1) Mouse mAb
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Gene ID
4292
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SwissProt ID
P40692
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Gene Name
MLH1
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Alternative Names
MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1
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Background
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human,Monkey
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Application
WB,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 85 kDa; Observed MW: 85 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
4C1-D9-C7
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Isotype
IgG1
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Immunogen
Purified recombinant fragment of MLH1 expressed in E. Coli.
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Purification
Ascitic Fluid
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Ascitic fluid containing 0.03% sodium azide.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.