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Product Name
SOD2 (4C4) Mouse mAb
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Gene ID
6648
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SwissProt ID
P04179
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Gene Name
SOD2
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Alternative Names
IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD; SOD2
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Background
SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. ROS are implicated in a wide range of degenerative processes, including Alzheimer’s disease, Parkinson’s disease and ischemic heart disease. Homozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiratory chain deficiencies in heart and skeletal muscle.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 25 kDa; Observed MW: 22 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
4C4-G8-H12
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Isotype
IgG2b
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Immunogen
Synthetic peptide corresponding to human SOD2 protein
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.