-
Product Name
Superoxide Dismutase 1 Mouse mAb
-
Gene ID
6647
-
SwissProt ID
P00441
-
Gene Name
SOD1
-
Alternative Names
ALS; SOD; ALS1; IPOA; homodimer
-
Background
SOD1 (superoxide dismutase 1, soluble), also known as ALS. The protein binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis (ALS), a progressive degenerative disease of motor neurons. Rare transcript variants have been reported for this gene.
-
Research Field
Signal Transduction
-
Product Categories
Primary antibody
-
Host
Mouse
-
Reactivity
Human,Mouse
-
Application
WB,ICC/IF,FC
-
Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
-
Molecular Weight
Calculated MW: 16 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
6D7-T3-T3
-
Isotype
Mouse IgG1
-
Immunogen
Purified recombinant fragment of human SOD1 expressed in E. Coli.
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Ascitic fluid containing 0.03% sodium azide.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.