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货号： 222743

别名： CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3

应用： WB,IHC-P,ICC/IF,ELISA

反应种属： Human

目录价格：

RMB(含税报价)

数量： - + （库存件）

查看代理商预计货期：3-4个工作日说明书PDF

产品详情

Product Name

SOCS3 Mouse mAb
Gene ID

9021
SwissProt ID

O14543
Gene Name

SOCS3
Alternative Names

CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3
Background

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
Research Field

Immunology
Product Categories

Primary antibody
Host

Mouse
Reactivity

Human
Application

WB,IHC-P,ICC/IF,ELISA
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200 ELISA: 1/10000
Molecular Weight

Calculated MW: 25 kDa;Observed MW: 30 kDa
Clonality

Monoclonal Antibody
Clonality No.

3E6-G3-U8
Isotype

Mouse IgG1
Immunogen

Purified recombinant fragment of human SOCS3 expressed in E. Coli.
Purification

Affinity Purified
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Purified antibody in PBS with 0.05% sodium azide
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

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