货号： 222739
别名： OCP2; p19A; EMC19; SKP1A; OCP-II; TCEB1L; MGC34403
应用： WB,IHC-P,ICC/IF,FC,ELISA
反应种属： Human
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    SKP1 Mouse mAb
  • Gene ID
    6500
  • SwissProt ID
    P63208
  • Gene Name
    SKP1
  • Alternative Names
    OCP2; p19A; EMC19; SKP1A; OCP-II; TCEB1L; MGC34403
  • Background
    This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
  • Research Field
    Cell Biology
  • Product Categories
    Primary antibody
  • Host
    Mouse
  • Reactivity
    Human
  • Application
    WB,IHC-P,ICC/IF,FC,ELISA
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200 FC: 1/50-1/100 ELISA: 1/10000
  • Molecular Weight
    Calculated MW: 19 kDa;Observed MW: 19 kDa
  • Clonality
    Monoclonal Antibody
  • Clonality No.
    4Y6-K3-H6
  • Isotype
    Mouse IgG1
  • Immunogen
    Purified recombinant fragment of human SKP1 expressed in E. Coli.
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    Ascitic fluid containing 0.03% sodium azide.
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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