产品详情
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Product Name
GADD45A (6C3) Mouse mAb
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Gene ID
1647
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SwissProt ID
P24522
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Gene Name
GADD45A
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Alternative Names
DDIT1; GADD45
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Background
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Transfected
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Application
WB
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Cited
WB (Human)
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 18 kDa; Observed MW: 22 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
6C3-G3-E9
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Isotype
IgG1
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Immunogen
Purified recombinant human GADD45 α protein expressed in E.coli
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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样本种属：
Human
杂 志：
ENVIRONMENTAL POLLUTION
应用：
WB
IF：
6.793
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