产品详情
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Product Name
RUNX1 Mouse mAb
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Gene ID
861
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SwissProt ID
Q01196
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Gene Name
RUNX1
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Alternative Names
AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1; RUNX1
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Background
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.
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Research Field
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,ICC/IF,ELISA
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 ELISA: 1/10000
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Molecular Weight
Calculated MW: 55kDa;Observed MW: 55kDa
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Clonality
Monoclonal Antibody
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Clonality No.
8M1-F4-L9
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Isotype
Mouse IgG1
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Immunogen
Synthesized peptide of human RUNX1.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Ascitic fluid containing 0.03% sodium azide.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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