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Product Name
CDK4 (3F9) Mouse mAb
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Gene ID
1019
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SwissProt ID
P11802
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Gene Name
CDK4
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Alternative Names
CMM3; PSK-J3
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Background
Cyclin-dependent kinase activity is regulated by T-loop phosphorylation (Thr172 in the case of CDK4), by the abundance of their cyclin partners, and by association with CDK inhibitors of the Cip/Kip or INK family of proteins. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human,Mouse,Rat
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 34 kDa; Observed MW: 34 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
3F9-B12-C8
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Isotype
IgG1
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Immunogen
Purified recombinant human CDK4 protein fragments expressed in E.coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.