产品详情
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Product Name
Fas (4C3) Mouse mAb
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Gene ID
355
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SwissProt ID
P25445
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Gene Name
FAS
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Alternative Names
FAS; ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6
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Background
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB
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Cited
IF (Human)
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 38 kDa; Observed MW: 45 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
4C3-G7-B7-H5
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Isotype
IgG1
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Immunogen
Purified recombinant human FAS (C-terminus) protein fragments expressed in E.coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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样本种属:
Human
杂 志:
MOLECULAR AND CELLULAR BIOLOGY
应用:
IF
IF:
5.036
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