产品详情
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Product Name
AP2M1 Mouse mAb
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Gene ID
1173
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SwissProt ID
Q96CW1
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Gene Name
AP2M1
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Alternative Names
mu2; AP50; CLAPM1
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Background
This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human,Monkey
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Application
WB,ELISA
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Dilution Ratio
WB: 1/500-1/1000 ELISA: 1/10000
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Molecular Weight
Calculated MW: 50 kDa;Observed MW: 50-70 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
6Z5-S8-N1
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Isotype
Mouse IgG1
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Immunogen
Purified recombinant fragment of human AP2M1 expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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