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货号： 340449

别名： GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B

应用： WB,IHC-F,IHC-P,ICC/IF,IP,ELISA

反应种属： Human,Mouse,Rat

目录价格：

RMB(含税报价)

数量： - + （库存件）

查看代理商预计货期：3-4个工作日说明书PDF

产品详情

Product Name

GSK3 beta Rabbit pAb
Gene ID

2932
SwissProt ID

P49841
Gene Name

GSK3B
Alternative Names

GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B
Background

Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis.
Research Field

Neuroscience
Product Categories

Primary antibody
Host

Rabbit
Reactivity

Human,Mouse,Rat
Application

WB,IHC-F,IHC-P,ICC/IF,IP,ELISA
Cited

WB (White king pigeon)
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 ELISA: 1/10000
Molecular Weight

Calculated MW: 47 kDa; Observed MW: 47 kDa
Clonality

Polyclonal Antibody
Clonality No.

-
Isotype

IgG
Immunogen

The antiserum was produced against synthesized peptide derived from human GSK3B.
Purification

Affinity Purified
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

引用文献更多完整详情

标题： A frog peptide provides new strategies for the intervention against skin wound healing

样本种属： Mouse，Rat

杂志： CELLULAR & MOLECULAR BIOLOGY LETTERS

应用： WB

IF： 8.3

文献链接

标题： Cancer/testis antigen PIWIL2 suppresses circadian rhythms by regulating the stability and activity of BMAL1 and CLOCK

样本种属： Mouse

杂志： Oncotarget

应用： WB

IF： 5.168

文献链接

标题： PIWIL1 suppresses circadian rhythms through GSK3β‐induced phosphorylation and degradation of CLOCK and BMAL1 in cancer cells

样本种属： Human

杂志： JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

应用： WB

IF： 4.658

文献链接

标题： Propranolol inhibits EMT and metastasis in breast cancer through miR-499-5p-mediated Sox6

样本种属： Mouse

杂志： JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

应用： WB

IF： 3.6

文献链接

标题： DL-methionine and DL-methionyl-DL-methionine Increase Intestinal Development and Activate Wnt/β-catenin Signaling Activity in Domestic Pigeons (Columba livia)

样本种属： White king pigeon

杂志： POULTRY SCIENCE

应用： WB

IF： 3.352

文献链接

标题： Downregulated KDM6A mediates gastric carcinogenesis via Wnt/β-catenin signaling pathway mediated epithelial-to-mesenchymal transition

样本种属： Human

杂志： PATHOLOGY RESEARCH AND PRACTICE

应用： WB

IF： 3.309

文献链接

标题： Hyperoxia exposure upregulates Dvl-1 and activates Wnt/β-catenin signaling pathway in newborn rat lung