-
Product Name
Angiopoietin 1 Rabbit pAb
-
Gene ID
284
-
SwissProt ID
Q15389
-
Gene Name
ANGPT1
-
Alternative Names
ANGPT1; KIAA0003; Angiopoietin-1; ANG-1
-
Background
Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Required for normal angiogenesis and heart development during embryogenesis. After birth, activates or inhibits angiogenesis, depending on the context.
-
Research Field
Cancer
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human,Rat
-
Application
WB,IHC-P,ELISA
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
-
Molecular Weight
Calculated MW: 58 kDa; Observed MW: 58 kDa
-
Clonality
Polyclonal Antibody
-
Clonality No.
-
-
Isotype
IgG
-
Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human ANGPT1.
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.