货号： 381155
别名： RPTOR; KOG1; KIAA1303; RAPTOR; Mip1
应用： WB,IHC-P,ICC/IF,FC,IP
反应种属： Human,Mouse,Rat
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：现货 说明书PDF
产品详情
  • Product Name
    Raptor Rabbit pAb
  • Gene ID
    57521
  • SwissProt ID
    Q8N122
  • Gene Name
    RPTOR
  • Alternative Names
    RPTOR; KOG1; KIAA1303; RAPTOR; Mip1
  • Background
    The regulatory associated protein of mTOR (Raptor) was identified as an mTOR binding partner that mediates mTOR signaling to downstream targets. Raptor binds to mTOR substrates, including 4E-BP1 and p70 S6 kinase, through their TOR signaling (TOS) motifs and is required for mTOR-mediated phosphorylation of these substrates. Binding of the FKBP12-rapamycin complex to mTOR inhibits the mTOR-raptor interaction, suggesting a mechanism for rapamycin's specific inhibition of mTOR signaling. This mTOR-raptor interaction and its regulation by nutrients and/or rapamycin is dependent on a protein called GβL.
  • Research Field
    Cell Biology
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human,Mouse,Rat
  • Application
    WB,IHC-P,ICC/IF,FC,IP
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/30 FC: 1/50-1/100
  • Molecular Weight
    Calculated MW: 149 kDa; Observed MW: 149 kDa
  • Clonality
    Polyclonal Antibody
  • Clonality No.
    -
  • Isotype
    IgG
  • Immunogen
    A synthesized peptide derived from human Raptor
  • Purification
    Affinity Chromatography
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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