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货号： 380865

别名： NRP1; NRP; VEGF165R; Neuropilin-1; Vascular endothelial cell growth factor 165 receptor; CD antigen CD304

应用： WB,IHC-P,ICC/IF,FC,IP

反应种属： Human,Mouse,Rat

目录价格：

RMB(含税报价)

数量： - + （库存件）

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产品详情

Product Name

Neuropilin 1 Rabbit pAb
Gene ID

8829
SwissProt ID

O14786
Gene Name

NRP1
Alternative Names

NRP1; NRP; VEGF165R; Neuropilin-1; Vascular endothelial cell growth factor 165 receptor; CD antigen CD304
Background

The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis.The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells.
Research Field

Cardiovascular
Product Categories

Primary antibody
Host

Rabbit
Reactivity

Human,Mouse,Rat
Application

WB,IHC-P,ICC/IF,FC,IP
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
Molecular Weight

Calculated MW: 103 kDa; Observed MW: 120 kDa
Clonality

Polyclonal Antibody
Clonality No.

-
Isotype

IgG
Immunogen

A synthesized peptide derived from human Neuropilin 1
Purification

Affinity Chromatography
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

引用文献更多完整详情

标题： An iRGD-conjugated prodrug micelle with blood-brain-barrier penetrability for anti-glioma therapy

样本种属： Human

杂志： BIOMATERIALS

应用： WB

IF： 10.273

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