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Product Name
Phospho-XIAP (Ser87) Rabbit pAb
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Gene ID
331
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SwissProt ID
P98170
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Gene Name
XIAP
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Alternative Names
API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3
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Background
This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 57 kDa; Observed MW: 57 kDa
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Clonality
Polyclonal Antibody
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Clonality No.
-
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Isotype
IgG
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Immunogen
Synthetic peptide of human XIAP
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.