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Product Name
Beta 2 Adrenergic Receptor Mouse mAb
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Gene ID
154
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SwissProt ID
P07550
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Gene Name
ADRB2
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Alternative Names
BAR; B2AR; ADRBR; ADRB2R; BETA2AR
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Background
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human,Rat
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Application
WB,FC,ELISA
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Dilution Ratio
WB: 1/500-1/1000 FC: 1/50-1/100 ELISA: 1/10000
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Molecular Weight
Calculated MW: 46 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
8O8-D5-B5
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Isotype
Mouse IgG1
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Immunogen
Purified recombinant fragment of human ADRB2 expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.