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货号： 222076

别名： CD276; B7-H3; B7RP-2; 4Ig-B7-H3

应用： IHC-P,ICC/IF,FC,ELISA

反应种属： Human

目录价格：

RMB(含税报价)

数量： - + （库存件）

查看代理商预计货期：3-4个工作日说明书PDF

产品详情

Product Name

CD276 Mouse mAb
Gene ID

80381
SwissProt ID

Q5ZPR3
Gene Name

B7H3
Alternative Names

CD276; B7-H3; B7RP-2; 4Ig-B7-H3
Background

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Field

Immunology
Product Categories

Primary antibody
Host

Mouse
Reactivity

Human
Application

IHC-P,ICC/IF,FC,ELISA
Dilution Ratio

IHC: 1/100-1/200 IF: 1/50-1/200 FC: 1/50-1/100 ELISA: 1/10000
Molecular Weight

-
Clonality

Monoclonal Antibody
Clonality No.

4J8-D7-J4
Isotype

Mouse IgG1
Immunogen

Purified recombinant fragment of human B7H3 expressed in E. Coli.
Purification

Affinity Purified
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Purified antibody in PBS with 0.05% sodium azide
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

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