货号： 222067
别名： AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1
应用： IHC-P,ICC/IF,FC,ELISA
反应种属： Human,Rat,Mouse,Monkey
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    ATM Mouse mAb
  • Gene ID
    472
  • SwissProt ID
    Q13315
  • Gene Name
    ATM
  • Alternative Names
    AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1
  • Background
    The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.
  • Research Field
    Epigenetics and Nuclear Signaling
  • Product Categories
    Primary antibody
  • Host
    Mouse
  • Reactivity
    Human,Rat,Mouse,Monkey
  • Application
    IHC-P,ICC/IF,FC,ELISA
  • Dilution Ratio
    IHC: 1/100-1/200 IF: 1/50-1/200 FC: 1/50-1/100 ELISA: 1/10000
  • Molecular Weight
    -
  • Clonality
    Monoclonal Antibody
  • Clonality No.
    4J1-A1-O4
  • Isotype
    Mouse IgG2b
  • Immunogen
    Purified recombinant fragment of human ATM expressed in E. Coli.
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    Purified antibody in PBS with 0.05% sodium azide
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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