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Product Name
ATG4C Mouse mAb
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Gene ID
84938
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SwissProt ID
Q96DT6
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Gene Name
ATG4C
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Alternative Names
APG4C; AUTL1; AUTL3; APG4-C
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Background
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,ELISA
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Dilution Ratio
WB: 1/500-1/1000 ELISA: 1/10000
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Molecular Weight
Calculated MW: 52 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
5D6-T4-H5
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Isotype
Mouse IgG1
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Immunogen
Purified recombinant fragment of human ATG4C expressed in E. Coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Purified antibody in PBS with 0.05% sodium azide
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.