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Product Name
SF3B3 Rabbit pAb
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Gene ID
23450
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SwissProt ID
Q15393
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Gene Name
SF3B3
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Alternative Names
SF3B3; KIAA0017; SAP130; Splicing factor 3B subunit 3; Pre-mRNA-splicing factor SF3b 130 kDa subunit; SF3b130; STAF130; Spliceosome-associated protein 130; SAP 130
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Background
Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB
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Cited
IF (Mouse); IP (Mouse )
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 136 kDa; Observed MW: 130 kDa
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Clonality
Polyclonal Antibody
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Clonality No.
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Isotype
IgG
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Immunogen
This SF3B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide from the C-terminal region of human SF3B3.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 0.09% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.