货号: 222017
别名: FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2
应用: IHC-P,ICC/IF,FC,ELISA
反应种属: Human
目录价格:
RMB(含税报价)
数量: - + (库存件)
查看代理商 预计货期:3-4个工作日 说明书PDF
产品详情
  • Product Name
    ACVR1 Mouse mAb
  • Gene ID
    90
  • SwissProt ID
    Q04771
  • Gene Name
    ACVR1
  • Alternative Names
    FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2
  • Background
    Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.
  • Research Field
    Signal Transduction
  • Product Categories
    Primary antibody
  • Host
    Mouse
  • Reactivity
    Human
  • Application
    IHC-P,ICC/IF,FC,ELISA
  • Dilution Ratio
    IHC: 1/100-1/200 IF: 1/50-1/200 FC: 1/50-1/100 ELISA: 1/10000
  • Molecular Weight
    -
  • Clonality
    Monoclonal Antibody
  • Clonality No.
    2R6-J4-R9
  • Isotype
    Mouse IgG1
  • Immunogen
    Purified recombinant fragment of human ACVR1 expressed in E. Coli.
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    Purified antibody in PBS with 0.05% sodium azide
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用,请参照上方的缩写含义,仔细对照后选择合适的产品。
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