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Product Name
ZO-1 tight junction protein Rabbit pAb
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Gene ID
7082
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SwissProt ID
Q07157
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Gene Name
TJP1
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Alternative Names
TJP1; ZO-1; tight junction protein 1;Tight junction protein ZO-1;Zona occludens protein 1;Zonula occludens protein 1
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Background
This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene. The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions.
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Research Field
Tags & Cell Markers
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Pig
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Application
WB,IHC-P
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Cited
WB (Mouse)
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Dilution Ratio
WB: 1/500-1/2000 IHC: 1/100-1/500
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Molecular Weight
Calculated MW: 195 kDa; Observed MW: 250 kDa
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Clonality
Polyclonal Antibody
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Clonality No.
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Isotype
IgG
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Immunogen
KLH conjugated synthetic peptide derived from human ZO-1
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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Storage
Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.