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Product Name
Transcription Factor E2 alpha Mouse mAb
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Gene ID
6929
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SwissProt ID
P15923
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Gene Name
TCF3
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Alternative Names
E2A; ITF1; VDIR; bHLHb21; MGC129647; MGC129648; TCF3
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Background
Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,FC
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Dilution Ratio
WB: 1/500-1/1000 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 68 kDa; Observed MW: 68 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
6B8
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Isotype
IgG1
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Immunogen
Purified recombinant fragment of human TCF3 expressed in E. Coli.
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Purification
Ascitic Fluid
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Ascitic fluid containing 0.03% sodium azide.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.